منابع مشابه
Skeletal muscle stem cells
Satellite cells are myogenic stem cells responsible for the post-natal growth, repair and maintenance of skeletal muscle. This review focuses on the basic biology of the satellite cell with emphasis on its role in muscle repair and parallels between embryonic myogenesis and muscle regeneration. Recent advances have altered the long-standing view of the satellite cell as a committed myogenic ste...
متن کاملMuscle stem cells at a glance
Muscle stem cells facilitate the long-term regenerative capacity of skeletal muscle. This self-renewing population of satellite cells has only recently been defined through genetic and transplantation experiments. Although muscle stem cells remain in a dormant quiescent state in uninjured muscle, they are poised to activate and produce committed progeny. Unlike committed myogenic progenitor cel...
متن کاملCellular Cardiomyoplasty Using Skeletal Muscle Stem Cells
Skeletal muscle satellite cells (myoblasts) are the primary stem cells of skeletal muscle which contribute to growth, maintenance, and repair of the muscle. Satellite cells offer several advantages for cellular cardiomyoplasty: can be easily obtained without affecting one’s function, vastly proliferated in culture, have high resistance to ischemic and hypoxic conditions, no identified risk for ...
متن کاملRegenerative medicine based on muscle stem cells.
and -4) as well as the angiogenic and anti-angiogenic factors (VEGF and sFLT-1). Interestingly, it has been observed that female MDSCs (F-MDSCs) can more efficiently regenerate the dystrophic skeletal muscle of mdx mice (a mouse model of Duchenne muscular dystrophy) than their male MDSCs (M-MDSCs) counterparts. Moreover, M-MDSCs when compared to F-MDSCs have been shown to be superior at bone an...
متن کاملStem cells for skeletal muscle repair.
Skeletal muscle is a highly specialized tissue composed of non-dividing, multi-nucleated muscle fibres that contract to generate force in a controlled and directed manner. Skeletal muscle is formed during embryogenesis from a subset of muscle precursor cells, which generate both differentiated muscle fibres and specialized muscle-forming stem cells known as satellite cells. Satellite cells rema...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Biology
سال: 2018
ISSN: 0960-9822
DOI: 10.1016/j.cub.2018.02.064